Railroads only allow one engineer's brake valve to be cut in and control a moving train. Some railroads allowed another one to be cut in while standing to assist charging a dry train in a yard.
Some rear helpers would not have the air cut in, generally just to push a train enough to get it started, then pull the pin and cutoff.
Modern locomotives equipped with Locotrol for DPU usually use the contolling remote locomotives to also control the brake pipe. The remote engines copy the lead engine. The only control the engineer has over the remotes is to cut their brakes in/out. This is one of the reasons these engines use the engineer's electronic brake valve.